Incyte has reached a European Union (EU) regulatory milestone in license agreement with Novartis for ruxolitinib.
Subscribe to our email newsletter
The recommendation by the CHMP of the EMA for approval of ruxolitinib to treat of disease-related splenomegaly or symptoms in adult patients with primary myelofibrosis, post-polycythemia vera myelofibrosis or post-essential thrombocythemia myelofibrosis has triggered the $40m payment.
Once Novartis achieves reimbursement and pricing approval in specific EU countries, a second $60m payment will be earned.
Ruxolitinib is known as Jakafi in the US and will be called Jakavi in Europe, the Incyte said.
In 2009, both the companies entered into a worldwide collaboration and license agreement under which Novartis gained exclusive rights for the development and commercialization of ruxolitinib in all hematology-oncology indications outside of the US.